Lundi 1er décembre 2014 de 11h à 12h, Vanessa Ezenwa (University of Georgia, Etats-Unis) présentera à la Tour du Valat (en grande salle) un séminaire en anglais intitulé « From host immunity to pathogen invasion: linking helminth co-infection and microparasite dynamics« .
L’accès à ce séminaire est libre et sans inscription.
Interactions between parasites co-occurring within a single host can have profound effects on the host response to infection. For instance, co-infection can affect the ability of a parasite to successfully establish within a host or influence the severity of infection experienced by the host. Although key immunological mechanisms underlying these within-host interactions between co-infecting parasites have been described, the ecological consequences of these interactions are poorly understood. In particular, it is unclear if and when interactions between co-infecting parasites can alter population level patterns of infectious disease.
In this talk, I discuss how immunological processes underlying parasite interactions within individual hosts can scale up to affect the population level dynamics of disease. I describe the results of a long-term field experiment testing whether co-infection with gastrointestinal helminths can alter the dynamics of bovine tuberculosis (BTB) in a wild reservoir host population. The study provides insight into the role that within-host processes can play in the distribution and spread of infectious diseases in the wild.